CBD, Cannabinoid & Hemp Research
Non-psychoactive cannabinoids (including CBD) have been studied extensively for almost three decades in animal models, see PubMed for thousands of independent studies, just a few are cited here.
Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects
British Journal of Pharmacology, Volume 163, Issue 7 – 19 Articles on Cannabinoids
Antitumorigenic Effects of Cannabinoids beyond Apoptosis
Beta-caryophyllene is a dietary cannabinoid
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb
Safety and side effects of cannabidiol, a Cannabis sativa constituent.
Effects of cannabidiol in animal models predictive of antipsychotic activity.
A Study of Infraspecific Flavonoid Variation of Cannabis Sativa L.
Phytocannabinoids beyond the Cannabis plant – do they exist?
A Chemotaxonomic Analysis of Cannabinoid Variation in Cannabis (Cannabaceae)
Cannabinoid and Terprnoid Reference Guide
Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts?
The draft genome and transcriptome of Cannabis sativa
Pharmacokinetics of cannabidiol in dogs
Cannabinoids reduce the progression of Alzheimer’s disease in animals
Cloning and pharmacological characterization of the dog cannabinoid CB₂ receptor.
Pharmacokinetics of the dimethylheptyl homolog of cannabidiol in dogs.
Comparative metabolism of cannabidiol in dog, rat and man.
CB₂: therapeutic target-in-waiting.
Phytocannabinoids and endocannabinoids.
Chemistry and Analysis of Phytocannabinoids and Other Cannabis Constituents
Delayed disease progression in ALS mice by treatment with a cannabinoid
Cardiovascular Pharmacology Time-dependent vascular actions of cannabidiol in the rat aorta
Industrial hemp decreases intestinal motility stronger than indian hemp in mice.
Cannabidiol and D9-THC are neuroprotective antioxidants
Neuroprotective antioxidants from marijuana
Cannabis Relieves Lou Gehrigs Symptoms
Prevention of Alzheimer’s Disease Pathology by Cannabinoids
Marijuana Slows Alzheimer’s Decline
Cannabinoids and the skeleton: from marijuana to reversal of bone loss.
Cannabinoids and bone: friend or foe?
Role of cannabinoids in the regulation of bone remodeling.
Cannabis in Palliative Medicine: Improving Care and Reducing Opioid-Related Morbidity
Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro.
The emerging role of the endocannabinoid system in cardiovascular disease.
The endocannabinoid system as a target for the treatment of neurodegenerative disease.
Marijuana Extract Helps Arthritis Pain
Rheumatoid arthritis, Cannabis based medicine eases pain and suppresses disease
Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning.
The endocannabinoid system and energy metabolism.
The emerging role of the endocannabinoid system in endocrine regulation and energy balance.
Endocannabinoid antagonism: blocking the excess in the treatment of high-risk abdominal obesity.
Cannabinoids in eating disorders and obesity.
[Cannabinoid system and feeding regulation]. [Spanish]
Endogenous cannabinoid system as a modulator of food intake.
The endocannabinoid system and the treatment of obesity.
Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood.
[Endocannabinoid system and energy metabolism: physiology and pathophysiology]. [Italian]
Cannabinoid receptors as therapeutic targets for obesity and metabolic diseases.
The endocannabinoid system, eating behavior and energy homeostasis: the end or a new beginning?
A Comparison of the Ocular and Central Effects of Δ9-Tetrahydrocannabinol and Cannabigerol.
The endocannabinoid system as a target for the treatment of motor dysfunction.
The endocannabinoid system in Huntington’s disease.
Prospects for cannabinoid therapies in basal ganglia disorders.
Cannabinoids and Parkinson’s disease.
Cannabinoids and neuroprotection in motor-related disorders.
Role of CB2 receptors in neuroprotective effects of cannabinoids.
Cannabinoids inhibit nitric oxide production in bone marrow derived feline macrophages.
Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study
[Cannabis and cannabinoids as drugs] Article in Norwegian.
Chemistry, metabolism, and toxicology of cannabis: clinical implications.
Pharmacological actions of cannabinoids.
Cannabinoids against pain. Efficacy and strategies to reduce psychoactivity: a clinical perspective.
Cannabinoid Receptors as Target for Treatment of Osteoporosis: A Tale of Two Therapies
The promise and dilemma of cannabinoid therapy: lessons from animal studies of bone disease
Marijuana in the management of amyotrophic lateral sclerosis
Cannabidiol-caused depression of spinal motoneuron responses in cats.
CB2 receptor-mediated antihyperalgesia: possible direct involvement of neural mechanisms.
Evidence for novel cannabinoid receptors.
Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders.
Therapeutic potential of cannabinoids in CNS disease.
The neurobiology and evolution of cannabinoid signalling.
Regulation of nausea and vomiting by cannabinoids.
Cannabinoid analgesia as a potential new therapeutic option in the treatment of chronic pain.
The cannabinoid system and pain: towards new drugs?]. [French]
Vascular targets for cannabinoids: animal and human studies
Human skin permeation of Delta8-tetrahydrocannabinol, cannabidiol and cannabinol.
The cannabinoids as potential antiepileptics.
Cannabinoids: Defending the Epileptic Brain
Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.
Marijuana treatments for autoimmune disorders
Cannabidivarin is anticonvulsant in mouse and rat.
Cannabinoids as potential new therapy for the treatment of gliomas
A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma
Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas
Cannabis: discrimination of “internal bliss”?
Cannabis: pharmacology and toxicology in animals and humans.
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
The pharmacology of cannabinoid receptors and their ligands: an overview.
Cannabinoids, immune system and cytokine network.
Targeting cannabinoid agonists for inflammatory and neuropathic pain.
Antineoplastic activity of cannabinoids.
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease
Cannabinoids Ameliorate Pain and Reduce Disease Pathology in Cerulein-Induced Acute Pancreatitis
Introduction to secondary metabolism in cannabis
Antimicrobial activity of flavonoids
The effects of dietary flavonoids on the regulation of redox inflammatory networks
Cannabis Finds Its Way into Treatment of Crohn’s Disease.
Marijuana Use Patterns Among Patients with Inflammatory Bowel Disease
Anti-inflammatory effects of Cannabinoid 2 Receptor activation in endotoxin-induced uveitis
Cannabidiol: An Overview of Some Pharmacological Aspects
Does Cannabidiol Protect Against Adverse Psychological Effects of THC?
Behavioral effects of cannabinoid agents in animals.
Endocannabinoids in liver disease.
Endocannabinoid chemical biology: a tool for the development of novel therapies.
In vitro metabolism of cannabichromene in seven common laboratory animals.
In vitro metabolism of cannabinol in rat, mouse, rabbit, guinea pig, hamster, gerbil and cat.
In vitro metabolism of cannabigerol in several mammalian species.
A Comparison of the Ocular and Central Effects of Δ9-Tetrahydrocannabinol and Cannabigerol
Comparative in vitro metabolism of the cannabinoids.
Role of 5-HT1 receptors of accumbens shell arenaupon ACPA-induced anxiolytic-like behaviors in rat
Endocannabinoids and the haematological system
Toward drugs derived from cannabis.
Inhibition of tumor angiogenesis by cannabinoids
Anticonvulsant properties of linalool
Limonene & How to Manage Symptoms of Gastroesophageal Reflux Disease
D-Limonene: safety and clinical applications.
Anticonvulsant properties of linalool in glutamate-related seizure models.
Cannabidiol arrests onset of autoimmune diabetes in NOD mice
Natural Products Evaluated in Neuropathic Pain Models – A Systematic Review
Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.
Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action.
Beneficial effects of a Cannabis sativa extract on diabetes induced neuropathy and oxidative stress
Marijuana: The Next Diabetes Drug?
Cannabinoids and the endocannabinoid system in lower urinary tract function and dysfunction.
Analysis of Cannabis Seizures in NSW, Australia: Cannabis Potency and Cannabinoid Profile
The cellular processing of the endocannabinoid anandamide and its pharmacological manipulation
Feasibility of Industrial Hemp Production in the United States Pacific Northwest
Industrial Hemp: Global Markets and Prices
Hemp as an Agricultural Commodity