Side Effects of Apoquel for Dogs

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It is tough to watch your dog itch and scratch like crazy in response to allergies that you can’t seem to control or even pin down a definitive cause for. It seems like your dog’s allergies are a constant aggravation. You might even fear they will never stop!  

Unfortunately, allergies are extremely common, so the chances of your dog developing an allergy to something at some point in his life is almost a given. That means you will be on the hunt for something effective that will help treat your dog’s allergy symptoms.

The primary symptom of allergies tends to be obsessive itching and scratching. Unfortunately, such behaviors can lead to other, secondary skin problems that will then need to be treated as well. These secondary symptoms can include redness, irritation, swelling, and hotspots on dogs.  

In many cases, dog owners often look to drugs intended for humans, such as Benadryl or Zyrtec as a potential relief measure. However, antihistamines like Zyrtec and Benadryl for dogs don’t always work, and they aren’t currently FDA approved for the treatment of allergies in dogs.

Other pet owners have sought to use steroid drugs like prednisone to help control symptoms, but that comes with its own set of dangers and challenges unique to steroidal medications.

In other cases, a dog owner may decide to go the natural route and search for alternative medications and remedies to provide their dog with some relief.

What is Apoquel for Dogs?

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Apoquel is a drug created by a company called Zoetis. It is the brand name for the drug called oclacitinib, that provides a new and targeted approach to interrupting the cycle of itching and inflammation that is associated with allergies in dogs.

Allergies in dogs can be related to food sensitivities, contact and environmental allergens, as well as atopic dermatitis. It is thought that around 10% of all dogs are affected by atopic dermatitis, and it is considered one of the most common allergy conditions dogs frequently suffer from.

Because allergies can affect a dog’s quality of life so much, finding a treatment option that helps you manage your dog’s symptoms is important. Allergies can range from short-term bouts of angst and itching, to acute conditions, to chronic and reoccurring ones. None are fun!

Apoquel is fairly fast-acting, and typically will offer relief within 4 hours of administering the medication. Once given to your dog, it can control symptoms such as itching for anywhere from 12 to 24 hours. Note however, that this drug is not intended for dogs under 12 months of age, or for dogs that weigh less than 6.6 pounds.

Benefits of Apoquel for Dogs

Obviously, the biggest benefit your dog will experience is temporary relief from the most maddening of allergy symptoms, obsessive itching. Apoquel begins to work within 4 hours, and begins to control itching within 24 hours.

How Does Apoquel Work for Dogs?

In “science speak”, Apoquel is called a “selective Janus kinase inhibitor” (or JAK for short). Kinases are compounds in a dog’s body that cells use for communicating information.

These JAKs are vital in regulating the body’s inflammatory response, as well as:

  • Controlling growth and development
  • Keeping your dog’s antibody cells and policing cells working properly
  • Forming red and white blood cells
  • Protecting the body against the formation of tumors

JAKs target itch-creating cytokines and suppresses the immune response to control scratching related to contact dermatitis, atopic dermatitis, flea allergies, and food allergies in dogs.

Apoquel is a drug that is fast-acting, and it helps to significantly reduce itching and inflammation both over the long-term as well as over the short-term.

However, even though this drug is fast-acting, it also may wear off fairly quickly, usually within a 12 to 24-hour period. This makes it a drug that must be given to your dog daily to effectively and consistently control allergy symptoms over a long period of time.

Symptoms of Allergies in Dogs

Dogs can suffer allergies related to a variety of different reasons. Environmental allergies, food allergies, and conditions like atopic dermatitis seem to be the most common.

If you aren’t sure your dog is suffering from allergies, look for common signs such as:

If you suspect your dog is suffering from allergies, see your vet to discuss appropriate methods of treatment or explore safe, more natural alternatives for dog allergies that do not require a prescription or an expensive vet visit.

Dosages of Apoquel for Dogs

The typical dose schedule of Apoquel for a dog is 0.4 – 0.6 mg/kg twice a day (every 12 hours) for up to 14 days. After that, the dosage may be reduced to 0.4 – 0.6 mg/kg once a day.

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Note that using Apoquel twice a day for longer than 14 days is not approved by the FDA. It is not advisable to exceed the dose that is recommended because of the way Apoquel suppresses the immune system.

Suppressing the immune system basically means you are treating your dog’s symptoms but doing nothing for the underlying cause of the condition. And by suppressing your dog’s immune system, it can make them vulnerable to other health concerns and illnesses.

Additionally, if you don&#